"I tried that supplement and felt nothing" is one of the most common reactions to nootropics, and it's often not because the ingredient doesn't work. It's because the dose was too low to do anything.
Ingredient research is done at specific doses. Below that threshold, an ingredient may produce little to no measurable effect, even if it's genuinely effective at the studied amount. Underdosing is common in the supplement industry for a straightforward reason: active ingredients are often the most expensive part of a formula, and cutting the dose is one of the easiest ways to reduce cost without changing the label.
A product can list an ingredient with strong research behind it, say, an adaptogen studied at a specific milligram amount for cortisol balance, while including a small fraction of that amount. The label isn't technically false. The dose is just too low to replicate what the research found.
This is part of why "I tried ashwagandha and it did nothing" and "clinical trials show ashwagandha supports cortisol balance" can both be true statements about different products.
Thesis formulas are dosed at up to 4x the industry standard for active ingredients, built around matching or approaching the doses used in the research behind each ingredient. A formula that's underdosed to hit a price point isn't doing what the label implies, even if every ingredient name on it is accurate.
Why did a supplement not work for me even though the research supports the ingredient? This is often a dosage issue rather than an ingredient issue. Many products include an ingredient at a fraction of the dose used in the research supporting it.
How do I know if a supplement is properly dosed? Check whether the label lists individual doses (not a proprietary blend total) and compare them to the doses used in published research for that ingredient, where available.
Does Thesis disclose exact doses? Yes. Every Thesis formula lists each ingredient individually with its specific dose, dosed at up to 4x the industry standard for active ingredients.
About Thesis: Thesis is a personalized nootropics brand backed by 9 years of research, 7.3 million data points, 30+ beta tests, and is third-party tested. takethesis.com
Results are from open-label consumer perception studies. Individual results may vary. See takethesis.com/pages/science for full study details.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Please consult a healthcare professional before starting any supplement. Thesis is for adults aged 18 and older.
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